Early Expression of Odorant Receptors Distorts the Olfactory Circuitry
نویسندگان
چکیده
منابع مشابه
Early expression of odorant receptors distorts the olfactory circuitry.
The odor response properties of a mammalian olfactory sensory neuron (OSN) are determined by the tightly regulated expression of a single member of a very large family of odorant receptors (ORs). The OR also plays an important role in focusing the central projections of all OSNs expressing that particular receptor to a pair of stereotypic locations (glomeruli) in each olfactory bulb (OB), thus ...
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Odorant receptors (ORs) belong to a large gene family of rhodopsin-like G protein-coupled receptors (GPCRs). The mouse OR gene family is composed of ∼1000 OR genes, and the human OR gene family is composed of ∼400 OR genes. The OR genes are spread throughout the genome, and can be found in clusters or as solitary genes in almost all chromosomes. These chemosensory GPCRs are expressed in highly ...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2010
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1502-10.2010